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Yakuzen Kusuri is the 5th girlfriend in The 100 Girlfriends Who Really, Really, Really, Really, Really Love You by Nozawa Yukiko.


In her normal teenage form, Kusuri has turquoise eyes and long, wavy red hair she keeps in a ponytail. She wears glasses, and has a slender build and a large bust. However, due to a failed experiment, she is in her child-like form most of the time. In this form, her hair is shorter, she does not need her glasses, and she tends to have a feline-like smile.


Kusuri is energetic and ingenuitive; she is capable of creating a drug for almost anything. She doesn't tend to be concerned about the dangers of the drugs she makes, and will often happily force them upon others or take them herself without hesitation.


Yakuzen Kusuri is Aijou Rentarou's 5th girlfriend.

Rentarou first saw her in her teenage form, but was unable to stop and meet her despite feeling the soulmate shock. They met properly when he later came to the classroom in search for her, but instead found her in her child form.

Kusuri attempted to make Rentarou drink a love drug, as she'd fallen in love with him at first sight, but didn't believe he'd feel the same way. However, Rentarou forced himself to vomit up the concoction and confess his love without the influence of any drugs.


She is highly proficient in chemistry, able to concoct drugs/medicine with various effects. Kusuri's drugs are even considered at the same level as Doraemon's. In Hahari's arc, Kusuri's drugs contribute a lot to the successfulness of the mission. However, sometimes her drugs bring trouble to Rentarou's family.




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e100 Kanojo
Media Manga
Story TimelineCharactersChapters and Volumes
Main Characters Aijou RentarouHanazono HakariInda KaraneYoshimoto ShizukaEiai NanoYakuzen KusuriHanazono HahariHaraga KurumiMeido MeiSutou IkuUtsukushisugi MimimiKakure MemeIin ChiyoYamato NadeshikoYasashiki YamameMomi MomijiYakuzen YakuTorotoro KishikaKedarui AashiiNakaji UtoMeido Mai
eList of Girlfriends
#1 to #5 Hanazono HakariInda KaraneYoshimoto ShizukaEiai NanoYakuzen Kusuri
#6 to #10 Hanazono HahariHaraga KurumiMeido MeiSutou IkuUtsukushisugi Mimimi
#11 to #15 Kakure MemeIin ChiyoYamato NadeshikoYasashiki YamameMomi Momiji
#16 to #20 Yakuzen YakuTorotoro KishikaKedarui AashiiNakaji UtoMeido Mai
Other Aijou RentarouAsakawaLove God